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2. Sleeping Pills (Sedative-Hypnotics)
Examples: Zolpidem (Ambien), Eszopiclone (Lunesta)
🧠 The problem: These medications depress the central nervous system, which can interfere with both memory formation and recall.
3. Benzodiazepines
Examples: Diazepam (Valium), Lorazepam (Ativan), Alprazolam (Xanax)
🧠 The problem: Studies have linked long-term use with increased risk of dementia and significant short-term memory problems.
4. Statins
Examples: Atorvastatin (Lipitor), Simvastatin (Zocor)
🧠 The problem: While not fully proven, there are concerns that statins may lower levels of cholesterol in the brain — which is essential for healthy nerve function.
5. Antidepressants (Tricyclics)
Older antidepressants like tricyclics are still prescribed today for depression, pain, and sleep disorders. But they also block acetylcholine, just like certain antihistamines.
6. Antipsychotics
Examples: Haloperidol (Haldol), Risperidone (Risperdal), Olanzapine (Zyprexa)
Used for schizophrenia, bipolar disorder, and severe depression, these drugs can be essential — but they also carry heavy side effects.
7. Anti-Seizure Medications
Examples: Phenytoin, Carbamazepine, Topiramate
These drugs calm the brain’s electrical activity to prevent seizures — but that calming effect can also slow down thinking and memory.
8. Incontinence Medications (Anticholinergics)
Examples: Oxybutynin (Ditropan), Tolterodine (Detrol)
🧠 The problem: Studies have shown that long-term use can significantly increase the risk of dementia.