“We don’t need another bad, tragic ending. We need some help,” Nanos said.

“This is an 84-year-old lady who suffers from some physical ailments, has some physical challenges, is in need of medication — medication that, if she doesn’t have in 24 hours, it could be fatal,”

The White House also urged the public to contact the police if they had information to share, as they took to Instagram, to highlight Nancy’s disappearance.

“The search for Savannah Guthrie’s mother, Nancy Guthrie, is ongoing, and authorities are requesting assistance from the public,” the administration wrote. “Anyone with information is urged to contact 911.

“Our prayers are with the Guthrie family as we hope for Nancy’s safe return home.”