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The version of genistein used in these experiments was considerably purer and more concentrated than what is available in typical dietary supplements. Wu acknowledged this distinction while noting the compound’s fundamental safety profile. “Nobody ever overdosed on tofu,” he remarked.
Broader Implications for mRNA Technology
The findings carry implications that extend beyond COVID-19 vaccination. The researchers suggest that elevated inflammatory cytokine signaling may be a general property of mRNA-based vaccines — a consequence of the body’s fundamental immune response to foreign genetic material.
